	US 12,226,416 B2
	Methods and materials for improving arteriovenous fistula maturation and maintaining arteriovenous fistula functionality
Karl A. Nath, Rochester, MN (US); James L. Kirkland, Rochester, MN (US); and Tamar Tchkonia, Rochester, MN (US)
Assigned to Mayo Foundation for Medical Education and Research, Rochester, MN (US)
Filed by Mayo Foundation for Medical Education and Research, Rochester, MN (US)
Filed on Feb. 5, 2024, as Appl. No. 18/432,824.
Application 18/432,824 is a division of application No. 16/973,723, granted, now 11,925,640, previously published as PCT/US2019/038569, filed on Jun. 21, 2019.
Claims priority of provisional application 62/688,822, filed on Jun. 22, 2018.
Prior Publication US 2024/0238289 A1, Jul. 18, 2024
Int. Cl. A61K 31/506 (2006.01); A61K 31/355 (2006.01); A61P 9/10 (2006.01)

CPC A61K 31/506 (2013.01) [A61K 31/355 (2013.01); A61P 9/10 (2018.01)]

16 Claims

1. A method for maintaining functionality of venous graft within a mammal, wherein said method comprises administering a composition comprising dasatinib, a tocotrienol, quercetin, or a combination thereof to said mammal, wherein said venous graft remains functional as effective graft following said administering step.