US 12,226,312 B2
Prosthetic heart valve
Nikolai Gurovich, Hadera (IL); Michael Bukin, Pardes Hanna (IL); Elena Sherman, Pardes Hana (IL); Tamir S. Levi, Zikhron Yaakov (IL); Ziv Yohanan, Kfar Hahoresh (IL); Gil Senesh, Laguna Beach, CA (US); Dikla Kersh, Karkur (IL); Alexey Tsypenyuk, Draper, UT (US); Waina Michelle Chu, Tustin, CA (US); and Alexander Barash, Tzoran (IL)
Assigned to EDWARDS LIFESCIENCES CORPORATION, Irvine, CA (US)
Filed by EDWARDS LIFESCIENCES CORPORATION, Irvine, CA (US)
Filed on May 12, 2023, as Appl. No. 18/316,942.
Application 18/316,942 is a continuation of application No. 17/316,885, filed on May 11, 2021.
Application 17/316,885 is a continuation of application No. 15/664,430, filed on Jul. 31, 2017, granted, now 11,096,781, issued on Aug. 24, 2021.
Claims priority of provisional application 62/369,678, filed on Aug. 1, 2016.
Prior Publication US 2023/0277313 A1, Sep. 7, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61F 2/24 (2006.01); A61F 2/90 (2013.01)
CPC A61F 2/2418 (2013.01) [A61F 2/2409 (2013.01); A61F 2/2433 (2013.01); A61F 2/2412 (2013.01); A61F 2/90 (2013.01); A61F 2220/0075 (2013.01); A61F 2230/0023 (2013.01); A61F 2230/0052 (2013.01); A61F 2250/0003 (2013.01); A61F 2250/0039 (2013.01); A61F 2250/0069 (2013.01); A61F 2310/00017 (2013.01); A61F 2310/00029 (2013.01); A61F 2310/00059 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A prosthetic heart valve, comprising:
a radially expandable and compressible frame having an inflow end and an outflow end, the frame comprising a plurality of struts defining openings between them;
a valvular structure comprising a plurality of leaflets, each leaflet comprising a main body having an inflow surface, an outflow surface opposing the inflow surface, an edge surface extending from the inflow surface to the outflow surface and defining a thickness of the leaflet, a coaptation edge portion, and a cusp edge portion, the cusp edge portion of each leaflet being folded toward the outflow end of the frame along a bending axis to form an outer fold layer that extends parallel to a longitudinal axis of the frame such that the edge surface faces the outflow end of the frame;
a reinforcing member separate from the frame extending along the bending axis between the outer fold layer and the outflow surface of the main body of each leaflet of the plurality of leaflets;
a plurality of connecting skirts, wherein each connecting skirt is disposed between the cusp edge portion of an adjacent leaflet and the frame;
first stitching securing the reinforcing member and the connecting skirts to the cusp edge portions of the leaflets; and
second stitching securing the connecting skirts to selected struts of the frame.