US 12,226,220 B2
Systems and methods for assessing sympathetic nervous system tone for renal neuromodulation therapy
Douglas Hettrick, Andover, MN (US); and Shantanu Sarkar, Roseville, MN (US)
Assigned to Medtronic Ireland Manufacturing Unlimited Company, Dublin (IE)
Filed by Medtronic Ireland Manufacturing Unlimited Company, Dublin (IE)
Filed on Jun. 1, 2023, as Appl. No. 18/327,426.
Application 18/327,426 is a continuation of application No. 16/885,574, filed on May 28, 2020, granted, now 11,707,220.
Application 16/885,574 is a continuation of application No. 15/526,472, granted, now 10,667,736, issued on Jun. 2, 2020, previously published as PCT/US2015/066469, filed on Dec. 17, 2015.
Claims priority of provisional application 62/093,933, filed on Dec. 18, 2014.
Claims priority of provisional application 62/093,383, filed on Dec. 17, 2014.
Prior Publication US 2023/0309902 A1, Oct. 5, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/00 (2006.01); A61B 5/024 (2006.01); A61B 5/0245 (2006.01); A61B 5/053 (2021.01); A61B 18/00 (2006.01); A61B 18/02 (2006.01); A61B 18/14 (2006.01); A61B 34/00 (2016.01); A61N 1/36 (2006.01); A61N 7/02 (2006.01); G16H 20/17 (2018.01); G16H 20/30 (2018.01); G16H 20/40 (2018.01); G16H 50/20 (2018.01); G16H 50/30 (2018.01)
CPC A61B 5/4035 (2013.01) [A61B 5/0245 (2013.01); A61B 18/1492 (2013.01); A61N 1/36017 (2013.01); G16H 20/30 (2018.01); G16H 20/40 (2018.01); G16H 50/20 (2018.01); G16H 50/30 (2018.01); A61B 5/00 (2013.01); A61B 5/02405 (2013.01); A61B 5/053 (2013.01); A61B 5/4836 (2013.01); A61B 2018/00404 (2013.01); A61B 2018/00434 (2013.01); A61B 2018/00511 (2013.01); A61B 2018/00773 (2013.01); A61B 2018/00839 (2013.01); A61B 2018/00875 (2013.01); A61B 2018/0212 (2013.01); A61B 2018/0262 (2013.01); A61B 2018/1435 (2013.01); A61B 2034/256 (2016.02); A61N 7/022 (2013.01); G16H 20/17 (2018.01)] 19 Claims
OG exemplary drawing
 
1. A system comprising:
a memory; and
one or more processors configured to:
determine a plurality of sympathetic nervous system (SNS) tone indicators based on cardiac data of a patient;
determine that an abnormality is present within the plurality of SNS tone indicators;
correct the abnormality within the plurality of SNS tone indicators;
compare an SNS tone indicator of the plurality of SNS tone indicators to a stored value stored in the memory;
determine that a neuromodulation therapy delivered to the patient was effective based on the comparison of the SNS tone indicator to the stored value.