US 12,226,167 B2
Systems and methods for use with MRI-guided focused ultrasound
Sean J. Nagel, Cleveland Heights, OH (US); Mark D. Bain, Cleveland, OH (US); Stephen Jones, Cleveland Heights, OH (US); and Shengqiang Gao, Beachwood, OH (US)
Assigned to The Cleveland Clinic Foundation, Cleveland, OH (US)
Filed by The Cleveland Clinic Foundation, Cleveland, OH (US)
Filed on Jul. 19, 2022, as Appl. No. 17/868,282.
Claims priority of provisional application 63/223,361, filed on Jul. 19, 2021.
Prior Publication US 2023/0017864 A1, Jan. 19, 2023
Int. Cl. A61B 34/20 (2016.01); A61B 17/22 (2006.01); G01R 33/48 (2006.01); A61B 90/00 (2016.01); A61M 25/00 (2006.01); A61M 25/06 (2006.01)
CPC A61B 34/20 (2016.02) [A61B 17/2202 (2013.01); G01R 33/4812 (2013.01); A61B 2017/22079 (2013.01); A61B 2017/22082 (2013.01); A61B 2034/2051 (2016.02); A61B 2090/3762 (2016.02); A61M 25/0026 (2013.01); A61M 2025/0681 (2013.01)] 27 Claims
OG exemplary drawing
 
1. A method of treatment comprising:
configuring a system for facilitating magnetic resonance-guided focused ultrasound aspiration to sonicate a body within an organ of a patient, the system comprising:
a transducer assembly comprising an array of ultrasound transducers adapted to deliver ultrasound energy, said transducer assembly at least partially defining a substantially liquid-tight jacket adapted to contain a fluid medium in order to conduct ultrasound waves; and
an access port adapted to accommodate therethrough a guide tube emerging from said jacket, said guide tube configured to permit passage of a catheter therethrough such that the catheter may be positioned adjacent to the body; and
sonicating the body with ultrasound energy supplied by at least one of the array of transducers of the system, thereby liquefying the body to produce liquified material; and
aspirating the liquified material via the catheter;
wherein said liquid tight jacket has been applied against and forms a seal with the patient such that said fluid medium is confined between the jacket and the patient, wherein both sonication of the body and positioning of the catheter adjacent thereto are assisted via image guidance, wherein said guide tube is made exclusively of substantially non-ferromagnetic materials.