| CPC A61B 18/02 (2013.01) [A61B 2018/00029 (2013.01); A61B 2018/00065 (2013.01); A61B 2018/00291 (2013.01); A61B 2018/00714 (2013.01); A61B 2018/0075 (2013.01); A61B 2018/0237 (2013.01)] | 17 Claims |

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1. A noninvasive medical device configured to provide cooling to a tissue region, the noninvasive medical device comprising:
a base including a top plate and a bottom plate opposite the top plate;
an inlet port and an outlet port arranged on the top plate;
a treatment surface arranged on the base and configured to engage the tissue region; and
a flow channel formed internal to the base and in fluid communication with the inlet port and the outlet port to form a closed circuit that isolates a working fluid from the tissue region, wherein the inlet port is configured to receive the working fluid and the flow channel is configured to promote evaporation of the working fluid to cool the base to a predetermined temperature.
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