	US 11,898,173 B2
	Recombinant acid-resistant yeast having improved lactic-acid-producing ability
Jae Yeon Park, Daejeon (KR); Tae Young Lee, Daejeon (KR); and Ki Sung Lee, Daejeon (KR)
Assigned to SK Innovation Co., Ltd., Seoul (KR)
Filed by SK INNOVATION CO., LTD., Seoul (KR)
Filed on Jun. 21, 2021, as Appl. No. 17/353,323.
Claims priority of application No. 10-2020-0077331 (KR), filed on Jun. 24, 2020.
Prior Publication US 2021/0403882 A1, Dec. 30, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. C12P 7/56 (2006.01); C12N 9/04 (2006.01)

CPC C12N 9/0006 (2013.01) [C12P 7/56 (2013.01); C12Y 101/01027 (2013.01)]

11 Claims

1. A recombinant strain having lactic-acid-producing ability, wherein the recombinant strain is constructed by deleting a gene encoding a pyruvate decarboxylase from the acid-resistant yeast YBC strain deposited under accession number KCTC13508BP and introducing in said acid-resistant yeast YBC strain deposited under accession number KCTC13508BP a gene encoding a lactate dehydrogenase derived from Staphylococcus epidermidis and comprising the sequence of SEQ ID NO: 1 at the position of the gene encoding the pyruvate decarboxylase.