	US 11,898,160 B2
	Method for maintaining pluripotency in cells
Cynthia C. Bamdad, Waltham, MA (US); and Shawn P. Fessler, Arlington, MA (US)
Assigned to MINERVA BIOTECHNOLOGIES CORPORATION, Waltham, MA (US)
Filed by Cynthia C. Bamdad, Waltham, MA (US); and Shawn P. Fessler, Arlington, MA (US)
Filed on Oct. 9, 2009, as Appl. No. 12/577,103.
Claims priority of provisional application 61/104,231, filed on Oct. 9, 2008.
Prior Publication US 2010/0093092 A1, Apr. 15, 2010
This patent is subject to a terminal disclaimer.
Int. Cl. C12N 5/0735 (2010.01); C12N 5/074 (2010.01)

CPC C12N 5/0606 (2013.01) [C12N 5/0696 (2013.01); C12N 2501/40 (2013.01); C12N 2501/50 (2013.01); C12N 2501/602 (2013.01); C12N 2501/603 (2013.01); C12N 2501/604 (2013.01); C12N 2501/998 (2013.01)]

18 Claims

1. A method for maintaining cell pluripotency or cell stemness, the method comprising:

contacting a cell characterized by an expression of OCT4 with an effective amount of an exogenous nucleoside diphosphate protein kinase 7 (NME7),

thereby maintaining the expression of the OCT4 in the cell.