CPC C07K 16/2896 (2013.01) [A61K 39/3955 (2013.01); A61P 37/00 (2018.01); C07K 16/22 (2013.01); A61K 39/39558 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2319/20 (2013.01)] | 13 Claims |
1. A method of treating a subject with a condition related to lung disease, wherein the lung disease is a disease of the airways, the method comprising administering to the subject a therapeutically effective amount of an antigen binding protein that specifically binds to a human Jagged1 polypeptide, wherein the antigen binding protein is an antibody or a fragment thereof, and wherein the antibody comprises a CDRL1, a CDRL2, a CDRL3, a CDRH1, a CDRH2, and a CDRH3, wherein CDRL1 comprises SEQ ID NO: 98, CDRL2 comprises SEQ ID NO: 99, CDRL3 comprises SEQ ID NO: 100, CDRH1 comprises SEQ ID NO: 230, CDRH2 comprises SEQ ID NO: 231, and CDRH3 comprises SEQ ID NO: 232.
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