US 11,897,950 B2
Osteopontin monoclonal antibodies
Kebin Liu, Augusta, GA (US); John Klement, Augusta, GA (US); and Priscilla S. Redd, Augusta, GA (US)
Assigned to Augusta University Research Institute, Inc., Augusta, GA (US); and Department of Veterans Affairs, Washington, DC (US)
Filed by Augusta University Research Institute, Inc., Augusta, GA (US); and Department of Veterans Affairs, Washington, DC (US)
Filed on Dec. 4, 2020, as Appl. No. 17/112,098.
Claims priority of provisional application 62/944,777, filed on Dec. 6, 2019.
Prior Publication US 2021/0188959 A1, Jun. 24, 2021
Int. Cl. C07K 16/24 (2006.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01)
CPC C07K 16/24 (2013.01) [A61K 45/06 (2013.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01); C07K 2319/30 (2013.01)] 8 Claims
 
1. A monoclonal antibody or antigen-binding fragment thereof that binds specifically to OPN, wherein the antibody comprises the heavy chain variable region (HCVR) sequences of SEQ ID NO:7, and the light chain variable region (LCVR) of SEQ ID NO:6.