CPC C07K 14/55 (2013.01) [A61K 38/00 (2013.01); C07K 2319/31 (2013.01); C07K 2319/33 (2013.01)] | 28 Claims |
1. An interleukin-2 polypeptide comprising an amino acid sequence of SEQ ID NO: 1, 2, 3, 4, or 5, wherein the interleukin-2 polypeptide comprises a replacement of the amino acid residues from positions 29 to 50 as set forth in SEQ ID NO: 1, 2, 3, 4, or 5 with a peptide comprising the amino acid sequence of an IL-15 hinge or a fragment thereof.
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