US 11,896,979 B2
Assay apparatuses, methods, and reagents
Gary I. Krivoy, Rockville, MD (US); Cecilia Zimmerman, Clarksburg, MD (US); Jules Vandersarl, Gaithersburg, MD (US); Sandor Kovacs, Middletown, DE (US); Aaron H. Leimkuehler, Upper St. Clair, PA (US); Leo Tabakin, Germantown, MD (US); Jon Willoughby, Gaithersburg, MD (US); Manish Kochar, Rockville, MD (US); and Charles M. Clinton, Clarksburg, MD (US)
Assigned to MESO SCALE TECHNOLOGIES, LLC., Rockville, MD (US)
Filed by Meso Scale Technologies, LLC., Rockville, MD (US)
Filed on Jul. 15, 2020, as Appl. No. 16/929,757.
Claims priority of provisional application 62/874,828, filed on Jul. 16, 2019.
Claims priority of provisional application 62/954,961, filed on Dec. 30, 2019.
Prior Publication US 2021/0016288 A1, Jan. 21, 2021
Int. Cl. B01L 9/00 (2006.01)
CPC B01L 9/523 (2013.01) [B01L 2300/0654 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/168 (2013.01); B01L 2300/1844 (2013.01); B01L 2300/1894 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An instrument comprising:
a light detection system having a housing, the light detection system comprising:
a CCD sensor and an optical lens system, wherein the light detection system is configured for positioning above a single well at a time in a multi-well plate to conduct an electrochemiluminescence analysis of the single well, wherein an area of the CCD sensor is approximately 1× to 2× of an area of the single well, and
a cooling element to cool the CCD sensor,
wherein the instrument further comprises a heat removal system comprising:
a first fan disposed in the light detection system and configured to pull heated air from the light detection system, and
a second fan connected to a cover manifold and oriented toward the top of the light detection system to pull the heated air into the cover manifold and out of the instrument.