US 11,896,945 B2
High surface area coatings for solid-phase synthesis
Bichlien Hoang Nguyen, Seattle, WA (US); Karin Strauss, Seattle, WA (US); and Hsing-Yeh Parker, Woodinville, WA (US)
Assigned to MICROSOFT TECHNOLOGY LICENSING, LLC, Redmond, WA (US)
Filed by MICROSOFT TECHNOLOGY LICENSING, LLC, Redmond, WA (US)
Filed on Oct. 9, 2019, as Appl. No. 16/597,799.
Prior Publication US 2021/0106967 A1, Apr. 15, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. B01J 19/00 (2006.01); C07K 1/04 (2006.01); C25D 17/10 (2006.01); C25D 5/48 (2006.01); C25D 5/16 (2006.01)
CPC B01J 19/0046 (2013.01) [C07K 1/042 (2013.01); C25D 5/16 (2013.01); C25D 5/48 (2013.01); C25D 17/10 (2013.01); B01J 2219/0059 (2013.01); B01J 2219/00497 (2013.01); B01J 2219/00596 (2013.01); B01J 2219/00612 (2013.01); B01J 2219/00722 (2013.01); B01J 2219/00725 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A stack for solid-phase polymer synthesis comprising:
a solid substrate having a surface;
a first coating on the surface that has a three-dimensional structure and which increases the usable surface area for polymer synthesis relative to the solid substrate, the first coating covering at least a portion of the surface of the solid substrate;
a second coating, in contact with the first coating, which further increases the usable surface area for polymer synthesis relative to the first coating, wherein the second coating comprises microparticles baked into a porous coating; and
a functional group attached to at least one of the first coating or the second coating.