US 11,896,792 B2
On-body microsensor for biomonitoring
Ashwin Pushpala, San Francisco, CA (US); Alan Szmodis, San Francisco, CA (US); Matthew Chapman, San Francisco, CA (US); Weldon Hall, San Francisco, CA (US); Scott Miller, San Francisco, CA (US); and Hooman Hafezi, San Francisco, CA (US)
Assigned to One Drop Biosensor Technologies, LLC, New York, NY (US)
Filed by ONE DROP BIOSENSOR TECHNOLOGIES, LLC, New York, NY (US)
Filed on Dec. 20, 2019, as Appl. No. 16/722,977.
Application 16/722,977 is a continuation of application No. 14/876,692, filed on Oct. 6, 2015, granted, now 10,549,080, issued on Feb. 4, 2020.
Application 14/876,692 is a continuation of application No. 14/211,404, filed on Mar. 14, 2014, granted, now 9,182,368, issued on Nov. 10, 2015.
Claims priority of provisional application 61/905,583, filed on Nov. 18, 2013.
Claims priority of provisional application 61/781,754, filed on Mar. 14, 2013.
Prior Publication US 2020/0121902 A1, Apr. 23, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/05 (2021.01); A61M 37/00 (2006.01); G01N 27/327 (2006.01); A61B 5/15 (2006.01); A61B 5/00 (2006.01); A61B 5/145 (2006.01); A61B 5/1486 (2006.01); A61B 5/1495 (2006.01); C12Q 1/00 (2006.01); A61M 25/00 (2006.01)
CPC A61M 37/0015 (2013.01) [A61B 5/1495 (2013.01); A61B 5/14503 (2013.01); A61B 5/14514 (2013.01); A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); A61B 5/14865 (2013.01); A61B 5/150022 (2013.01); A61B 5/150282 (2013.01); A61B 5/150427 (2013.01); A61B 5/150969 (2013.01); A61B 5/150984 (2013.01); A61B 5/4839 (2013.01); A61B 5/685 (2013.01); C12Q 1/006 (2013.01); G01N 27/3271 (2013.01); A61B 2562/028 (2013.01); A61B 2562/12 (2013.01); A61B 2562/125 (2013.01); A61M 25/00 (2013.01); A61M 2037/0023 (2013.01); A61M 2037/0046 (2013.01); A61M 2037/0053 (2013.01); Y10T 29/49117 (2015.01)] 33 Claims
OG exemplary drawing
 
1. A sensor for sensing analytes present in a body fluid of a user, the sensor comprising:
a substrate; and
a filament attached to the substrate and configured to provide access to the body fluid comprising:
a substrate core comprising:
a columnar protrusion having a base end, coupled to the substrate, and a distal portion operable to provide access to the body fluid of the user during operation of the sensor;
a conductive layer, isolated to the distal portion of the substrate core and away from the base end as an active region operable to transmit electronic signals generated upon detection of an analyte within the body fluid;
an insulating layer surrounding the substrate core and exposing a portion of the conductive layer at the distal portion; and
a sensing layer, in communication with the active region, configured for at least one of amperometric sensing and potentiometric sensing of the analyte.