US 11,896,723 B2
Microcell systems for delivering benefit agents
Lei Liu, Fremont, CA (US)
Assigned to E INK CORPORATION, Billerica, MA (US)
Filed by E INK CORPORATION, Billerica, MA (US)
Filed on Oct. 20, 2021, as Appl. No. 17/505,798.
Claims priority of provisional application 63/107,170, filed on Oct. 29, 2020.
Prior Publication US 2022/0133644 A1, May 5, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 9/70 (2006.01)
CPC A61K 9/7084 (2013.01) [A61K 9/7092 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A benefit agent delivery system including a layer of microcells, the layer of microcells comprising:
a plurality of a first type of microcells filled with a first formulation comprising a first benefit agent in a carrier, wherein the carrier of the first formulation comprises a first organic solvent;
a plurality of a second type of microcells filled with a second formulation comprising a second benefit agent in a carrier, wherein the carrier of the second formulation comprises a second organic solvent, wherein the first and second benefit agents are different, and wherein the first benefit agent is not compatible with the second benefit agent;
a plurality of a third type of microcells that do not contain a formulation comprising a benefit agent;
wherein each microcell of the pluralities of the first, second, and third types of microcells includes walls and an opening;
wherein each microcell of the pluralities of the first and second types of microcells includes a sealing layer spanning the opening;
wherein the plurality of the third type of microcells does not include a sealing layer spanning the opening;
wherein the benefit agent delivery system comprises one or more segments of the first type of microcells, wherein each segment of the first type of microcells consisting of microcells of the first type of microcells, and all the microcells of the first type of microcells that adjacent to any other microcell of the segment of the first type of microcells are members of the same segment;
wherein the periphery of each segment of the first type of microcells is surrounded by microcells of the third type of microcells;
wherein the benefit agent delivery system comprises one or more segments of the second type of microcells, wherein each segment of the second type of microcells consisting of microcells of the second type of microcells, and all the microcells of the second type of microcells that are adjacent to any other microcell of the segment of the second type of microcells are members of the same segment;
wherein the periphery of each segment of the second type of microcells is surrounded by microcells of the third type of microcells, and
wherein each of the first type of microcells is separated from any microcell of the second type of microcells by the third type of microcells.