US 11,896,720 B2
Orally available articles containing at least one stabilized supplement therein
Timothy Brian Chiprich, Huntington Beach, CA (US); Argelia Sinay Melendez, Montebello, CA (US); Bibu Philip George, Norwalk, CA (US); David Wood, Yorba Linda, CA (US); Jangsoon Park, Cypress, CA (US); Jung Ku Cho, La Palma, CA (US); Lilyan Hong Tran, Fountain Valley, CA (US); Paul Hwang, Fullerton, CA (US); and Ronnie Bayless, Cerritos, CA (US)
Assigned to CAPTEK SOFTGEL INTERNATIONAL, Cerritos, CA (US)
Filed by Captek Softgel International, Cerritos, CA (US)
Filed on Sep. 25, 2018, as Appl. No. 16/141,070.
Claims priority of provisional application 62/563,562, filed on Sep. 26, 2017.
Prior Publication US 2019/0091159 A1, Mar. 28, 2019
Int. Cl. A61K 9/50 (2006.01); A23L 33/135 (2016.01); A61K 9/48 (2006.01); A23P 10/30 (2016.01); A23G 1/00 (2006.01); A23K 50/20 (2016.01); A23K 20/10 (2016.01); A23L 33/105 (2016.01); A61K 9/00 (2006.01); A23K 20/174 (2016.01); A23K 50/30 (2016.01); A23K 50/50 (2016.01); A23K 50/70 (2016.01); A23K 50/40 (2016.01); A23K 10/18 (2016.01); A61K 47/36 (2006.01); A23L 29/206 (2016.01); A61K 31/715 (2006.01)
CPC A61K 9/5057 (2013.01) [A23G 1/00 (2013.01); A23K 10/18 (2016.05); A23K 20/10 (2016.05); A23K 20/174 (2016.05); A23K 50/20 (2016.05); A23K 50/30 (2016.05); A23K 50/40 (2016.05); A23K 50/50 (2016.05); A23K 50/70 (2016.05); A23L 33/105 (2016.08); A23L 33/135 (2016.08); A23P 10/30 (2016.08); A61K 9/0056 (2013.01); A61K 9/4808 (2013.01); A61K 9/4833 (2013.01); A61K 9/4858 (2013.01); A61K 9/4891 (2013.01); A23L 29/206 (2016.08); A61K 31/715 (2013.01); A61K 47/36 (2013.01)] 19 Claims
 
1. An orally available softgel comprising:
a liquid fill material comprising:
a pre-wetted probiotic comprising a probiotic and an edible oil, wherein the edible oil is present in a range of 25% to 75% by weight of a total weight of the probiotic and edible oil; and
a stabilizing component derived from cacao seeds selected from the group consisting of chocolate liquor, milk chocolate, white chocolate, dark chocolate, cocoa nib paste, cocoa solid, cocoa flavanol, and combinations thereof as a balance of the fill material;
wherein the edible oil is present in an amount sufficient to reduce a melting point temperature of the stabilizing component and edible oil mixture to below 40° C., and
a softgel capsule shell surrounding the fill material, the softgel capsule shell comprising a plasticizer and 7% to 15% by weight water;
wherein upon cooling the liquid fill material becomes a solid and the stabilizing component protects the probiotic from the deleterious effects of the water in the softgel capsule shell.