US 11,896,633 B2
Homogeneous engineered phage populations
Angela M. Belcher, Lexington, MA (US); Uyanga Tsedev, Somerville, MA (US); and Fred Lam, Brookline, MA (US)
Assigned to Massachusetts Institute of Technology, Cambridge, MA (US)
Filed by Massachusetts Institute of Technology, Cambridge, MA (US)
Filed on Mar. 22, 2021, as Appl. No. 17/208,256.
Application 17/208,256 is a continuation of application No. 16/040,793, filed on Jul. 20, 2018, granted, now 10,987,388.
Claims priority of provisional application 62/535,604, filed on Jul. 21, 2017.
Prior Publication US 2021/0205381 A1, Jul. 8, 2021
Int. Cl. A61K 35/76 (2015.01); A61K 47/69 (2017.01); A61K 47/64 (2017.01); A61K 9/00 (2006.01); C12N 7/00 (2006.01); C12N 15/70 (2006.01); C12N 15/861 (2006.01); A61K 49/00 (2006.01)
CPC A61K 35/76 (2013.01) [A61K 47/6901 (2017.08); C12N 7/00 (2013.01); C12N 15/70 (2013.01); C12N 15/861 (2013.01); A61K 9/0019 (2013.01); A61K 47/6415 (2017.08); A61K 49/0021 (2013.01); C12N 2795/14121 (2013.01); C12N 2795/14122 (2013.01); C12N 2795/14131 (2013.01); C12N 2795/14132 (2013.01); C12N 2800/202 (2013.01); C12N 2810/40 (2013.01)] 43 Claims
 
1. A homogeneous engineered filamentous phage population, wherein at least 30% of filamentous phages in the phage population have a length within 15% of a selected length value, which is greater than the corresponding wild type filamentous phage length value and up to 10 microns.