US 11,896,380 B2
Medical decision support system
Sergey A. Telenkov, Ottawa (CA); Robin F. Castelino, Kanata (CA); David Gloag, Kanata (CA); Daniel Labonté, Ottawa (CA); and Md Shahidul Islam, Ottawa (CA)
Assigned to AUSCULSCIENCES, INC., Vienna, VA (US)
Filed by AUSCULSCIENCES, INC., Vienna, VA (US)
Filed on Feb. 23, 2022, as Appl. No. 17/679,072.
Application 17/679,072 is a continuation of application No. 16/854,894, filed on Apr. 21, 2020, granted, now 11,284,827.
Application 16/854,894 is a continuation in part of application No. PCT/US2018/056956, filed on Oct. 22, 2018.
Claims priority of provisional application 62/838,270, filed on Apr. 24, 2019.
Claims priority of provisional application 62/838,296, filed on Apr. 24, 2019.
Claims priority of provisional application 62/575,390, filed on Oct. 21, 2017.
Claims priority of provisional application 62/575,399, filed on Oct. 21, 2017.
Claims priority of provisional application 62/575,397, filed on Oct. 21, 2017.
Prior Publication US 2022/0175298 A1, Jun. 9, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/02 (2006.01); A61B 5/352 (2021.01); A61B 5/316 (2021.01)
CPC A61B 5/352 (2021.01) [A61B 5/316 (2021.01)] 28 Claims
OG exemplary drawing
 
1. A method of segmenting an auscultatory sound signal, comprising:
a. receiving an electrographic signal from an ECG sensor;
b. generating an electrographic envelope signal representing an envelope responsive to an even power of said electrographic signal;
c. locating a plurality of peaks of said electrographic envelope signal corresponding to a corresponding plurality of R-peaks of said electrographic signal;
d. receiving at least one auscultatory sound signal from a corresponding at least one auscultatory sound-or-vibration sensor;
e. filtering said at least one auscultatory sound signal with a high-pass filter so as to generate a corresponding at least one high-pass-filtered auscultatory sound signal;
f. segmenting said corresponding at least one high-pass-filtered auscultatory sound signal into at least one heart-cycle segment responsive to said plurality of peaks of said electrographic envelope signal;
g. for each one said at least one heart-cycle segment:
i. generating an auscultatory envelope signal representing an envelope responsive to an even power of said auscultatory sound signal within said one said at least one heart-cycle segment;
ii. locating at least a second peak of said auscultatory envelope signal corresponding to a second heart sound;
iii. generating a local mathematical model of at least said second peak of said auscultatory envelope signal, wherein said local mathematical model comprises a quadratic equation; and
iv. locating at least one root selected from the group consisting of a first root of said local mathematical model and a second root of said local mathematical model, so as to provide for determining an associated start of diastole of said one said at least one heart-cycle segment.