US 11,896,309 B2
Retina imaging system based on the common beam scanning
Yi He, Jiangsu (CN); Guohua Shi, Jiangsu (CN); Feng Gao, Jiangsu (CN); Wen Kong, Jiangsu (CN); Lina Xing, Jiangsu (CN); Wanyue Li, Jiangsu (CN); Jing Wang, Jiangsu (CN); and Xin Zhang, Jiangsu (CN)
Assigned to SUZHOU INSTITUTE OF BIOMEDICAL ENGINEERING AND TECHNOLOGY, CHINESE ACADEMY OF SCIENCES, Suzhou (CN)
Appl. No. 16/971,570
Filed by Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Jiangsu (CN)
PCT Filed Oct. 22, 2019, PCT No. PCT/CN2019/112521
§ 371(c)(1), (2) Date Aug. 20, 2020,
PCT Pub. No. WO2021/046973, PCT Pub. Date Mar. 18, 2021.
Claims priority of application No. 201910865740.4 (CN), filed on Sep. 9, 2019.
Prior Publication US 2023/0094588 A1, Mar. 30, 2023
Int. Cl. A61B 3/10 (2006.01); A61B 3/12 (2006.01); A61B 3/15 (2006.01)
CPC A61B 3/1025 (2013.01) [A61B 3/1015 (2013.01); A61B 3/12 (2013.01); A61B 3/152 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A common beam scanning retinal imaging system, characterized in that, the system comprises: a light source module, an adaptive optics module, a beam scanning module, a small field-of-view relay module, a large field-of-view relay module, a sight beacon module, a pupil monitoring module, a detection module, a control module and an output module;
the light source module is configured to emit a parallel light beam with at least two different wavelengths, wherein the parallel light beam irradiates a human eye after going through the adaptive optics module, the beam scanning module, and the small field-of-view relay module or the large field-of-view relay module sequentially, imaging light that is scattered by the human eye and carries aberration information of the human eye and light intensity information returns along an original optical path of the parallel light beam and reaches the adaptive optics module and the detection module;
the adaptive optics module is configured to receive the imaging light carrying the aberration information of the human eye, and perform real-time measurement and correction of wavefront aberration;
the beam scanning module includes a biaxial scanning mirror which is connected to the adaptive optics module through a first transmissive or reflective telescope along an incident end of the optical path and is connected to the small field-of-view relay module or the large field-of-view relay module through a second transmissive or reflective telescope along an exit end of the optical path, so as to achieve a small field-of-view high-resolution imaging and a large field-of-view low-resolution imaging, respectively;
the small field-of-view relay module is configured as a beam expanding telescope, and the large field-of-view relay module is configured as a beam contracting telescope;
the sight beacon module is configured to guide and fix a sight beacon of the human eye;
the pupil monitoring module is configured to align and monitor a pupil of the human eye;
the detection module is configured to receive the returning imaging light of the human eye, convert the imaging light into an electrical signal, and transmit the electrical signal to the control module; and
the output module is configured to connect to the control module, and display and store imaging images of the human eye;
wherein the system further comprises a dichroic beam splitter module including a first dichroic beam splitter, a second dichroic beam splitter, a third dichroic beam splitter and a fourth dichroic beam splitter arranged successively along an incident optical path;
the light source module includes a light source, a collimator and a first beam splitter arranged successively along the incident optical path, and is configured to output a parallel light beam to the adaptive optics module, wherein the light emitted by the light source passes through the collimator, and is then partially transmitted through the first beam splitter to enter the adaptive optics module;
the adaptive optics module includes a wavefront corrector, a second beam splitter, an optical filter and a wavefront sensor arranged successively along a returning optical path of human eye imaging, and is connected to the beam scanning module; wherein the parallel light beam outputted by the light source module is reflected to the beam scanning module by the wavefront corrector; wherein the returning imaging light carrying the aberration information of the human eye and the light intensity information exits from the beam scanning module and is reflected to the first beam splitter by the wavefront corrector, one part of the light reflected by the first beam splitter is then reflected by the second beam splitter, passes through the optical filter, and then reaches the wavefront sensor, so as to realize measurement of wavefront aberration, and the other part of the light reflected by the first beam splitter is transmitted through the second beam splitter and enters the detection module; and
the wavefront sensor is configured to receive an imaging light beam containing the aberration information of the human eye and transmit the aberration information to the control module, the control module is configured to perform wavefront calculation, detect wavefront aberration, obtain a wavefront control voltage and output the wavefront control voltage to the wavefront corrector, and the wavefront corrector is configured to correct the wavefront aberration.