US 11,896,294 B2
Method and systems for reducing treatment variability and increasing treatment efficacy and durability
Philip J. Johnson, Plymouth, MN (US); Ryan Kaveckis, Minneapolis, MN (US); and Martin L. Mayse, Wayzata, MN (US)
Assigned to Nuvaira, Inc., Plymouth, MN (US)
Appl. No. 16/467,426
Filed by Nuvaira, Inc., Plymouth, MN (US)
PCT Filed Dec. 7, 2017, PCT No. PCT/US2017/065149
§ 371(c)(1), (2) Date Jun. 6, 2019,
PCT Pub. No. WO2018/106939, PCT Pub. Date Jun. 14, 2018.
Claims priority of provisional application 62/431,283, filed on Dec. 7, 2016.
Prior Publication US 2020/0222114 A1, Jul. 16, 2020
Int. Cl. A61B 18/14 (2006.01); A61B 18/00 (2006.01)
CPC A61B 18/1492 (2013.01) [A61B 2018/0072 (2013.01); A61B 2018/00541 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00678 (2013.01); A61B 2018/00702 (2013.01); A61B 2018/00755 (2013.01); A61B 2018/00821 (2013.01); A61B 2018/00886 (2013.01); A61B 2018/00898 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A system for ablating target tissue of an airway of a patient during a treatment, the system comprising:
an ablation assembly, the ablation assembly being configured to be positioned within the airway, the ablation assembly including an active energy emitter configured to contact an airway wall of the airway, and wherein the active energy emitter is configured to deliver energy to the target tissue of the airway to ablate the target tissue, the target tissue being spaced radially outward from the energy emitter; and
a controller configured to control energy delivery from an energy source to the energy emitter, wherein the controller is configured to modify one of power and current of the system to achieve a predetermined output value during at least a portion of a treatment time,
wherein the predetermined output value is a current target, wherein an impedance of tissue at an energy emitter tissue interface is measured during the treatment time, and wherein the controller is configured to:
hold the current constant if a predetermined impedance target is reached before the current target is reached; or
vary the power to achieve the current target if the predetermined impedance target is not met during the treatment time,
wherein the predetermined impedance target is a percent impedance drop calculated by:

OG Complex Work Unit Math
in which RTO is an impedance at a beginning of the treatment time, and RTactual is an impedance at a time t during the treatment time.