US 12,224,061 B2
Determining levels of hypertension from retinal vasculature images
Gavin Robertson, Dunfermline (GB); and Alan Duncan Fleming, Dunfermline (GB)
Assigned to OPTOS PLC, Dunfermline (GB)
Filed by OPTOS PLC, Dunfermline (GB)
Filed on Apr. 1, 2020, as Appl. No. 16/837,733.
Claims priority of application No. 19167391 (EP), filed on Apr. 4, 2019.
Prior Publication US 2020/0320693 A1, Oct. 8, 2020
Int. Cl. G16H 50/20 (2018.01); G06T 5/40 (2006.01); G06T 7/00 (2017.01); G06T 7/11 (2017.01); G06T 7/155 (2017.01); G06V 10/764 (2022.01); G06V 10/82 (2022.01); G06V 40/18 (2022.01); G16H 30/40 (2018.01); G16H 50/30 (2018.01)
CPC G16H 50/20 (2018.01) [G06T 5/40 (2013.01); G06T 7/0012 (2013.01); G06T 7/11 (2017.01); G06T 7/155 (2017.01); G06V 10/764 (2022.01); G06V 10/82 (2022.01); G06V 40/193 (2022.01); G16H 30/40 (2018.01); G16H 50/30 (2018.01); G06T 2207/20024 (2013.01); G06T 2207/20036 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/30041 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A non-transitory, computer-readable storage medium storing computer program instructions which, when executed by a computer, cause the computer to execute a method for determining a level of hypertension of a person, said method comprising:
acquiring image data defining a retinal image of a retina of the person that has been captured by a retinal imaging system;
processing the image data based on a classification algorithm, which has been trained on image data defining retinal images of a plurality of subjects, to identify a plurality of vessel segments present in the retinal image, wherein the processing comprises:
demarcating a region of interest, which is confined to a portion of the retinal image showing a near periphery of the retina that comprises an annular segment subtending 180 degrees nasal to the optic disc, from a remainder of the retinal image; and
processing the image data to identify the plurality of vessel segments in the region of interest of the retinal image;
determining respective widths of vessel segments of at least a subset of the plurality of vessel segments present in the region of interest of the retinal image;
calculating, as at least one value of a vascular summary metric, at least one of an average value of and a median value of the determined widths of the vessel segments present in the region of interest of the retinal image; and
using the at least one value of the vascular summary metric and a relationship between the vascular summary metric and a level of hypertension to determine a level of hypertension by which the person has been affected.