US 12,223,854 B2
Device specific finite element models for simulating endovascular treatment
Mohamed Haithem Babiker, Tempe, AZ (US); David H. Frakes, Scottsdale, AZ (US); and Brian W. Chong, Scottsdale, AZ (US)
Assigned to Mayo Foundation for Medical Education and Research, Scottsdale, AZ (US); and Arizona Board of Regents on Behalf of Arizona State University, Rochester, MN (US)
Filed by Arizona Board of Regents on Behalf of Arizona State University, Scottsdale, AZ (US); and Mayo Foundation for Medical Education and Research, Rochester, MN (US)
Filed on Apr. 26, 2019, as Appl. No. 16/396,005.
Application 16/396,005 is a continuation of application No. 14/605,887, filed on Jan. 26, 2015, granted, now 10,290,230.
Claims priority of provisional application 61/996,972, filed on May 22, 2014.
Claims priority of provisional application 61/996,971, filed on Jan. 27, 2014.
Prior Publication US 2019/0251866 A1, Aug. 15, 2019
This patent is subject to a terminal disclaimer.
Int. Cl. G09B 23/28 (2006.01); G09B 5/02 (2006.01)
CPC G09B 23/28 (2013.01) [G09B 5/02 (2013.01); G09B 23/285 (2013.01)] 21 Claims
 
1. A system for simulating medical device dynamics, the system comprising:
a database configured to store medical device models of different sized flow diverters, each model comprising a plurality of braided strands, each strand being represented by a plurality of serially linked beam elements with a virtual diameter that is equal to a diameter of the strand;
a user interface configured to receive clinical data of a patient, wherein the user interface is configured to allow a user to select a plurality of the medical device models from the database; and
one or more processors configured to:
virtually construct each of the medical device models by modeling the plurality of braided strands to have a pitch and a number of clockwise and anti-clockwise strands;
virtually construct an anatomical structure model of the patient;
simulate a deployment of the plurality of the medical device models in the anatomical structure model by:
modeling crimping of each medical device model of the plurality of medical device model into a shape of a microcatheter by imposing one or more radial displacement boundary conditions applied in time using a smooth step function; and
modeling advancing of each crimped medical device model along a centerline of a vessel of the anatomical structure model by applying displacement boundary conditions to nodes at a distal tip of the virtual microcatheter to guide the virtual microcatheter along the centerline of the vessel to a treatment region of the anatomical structure model, and generating at least one surface mesh and at least one blood volume mesh by (1) sweeping the beam elements of each strand of the medical device model with a circular surface having the diameter of the strand, and (2) applying an Octree mesh filing technique to the at least one blood volume;
modeling unsheathing of each crimped medical device model;
simulate hemodynamic outcomes after simulating the deployment of the plurality of the medical device models in the anatomical structure model;
generate a report comprising one or more of hemodynamic outcome data and medical device model performance data; and
select a medical device for use in an endovascular medical device placement procedure based at least in part on one or more of the hemodynamic outcome data and the medical device model performance data.