US 12,223,754 B2
Automatic calibration using machine learning
Yonggang Jiang, Dorset (GB)
Assigned to Advanced Instruments Ltd., Dorset (GB)
Filed by SOLENTIM LTD., Dorset (GB)
Filed on Jun. 7, 2022, as Appl. No. 17/834,803.
Claims priority of application No. 2108153 (GB), filed on Jun. 8, 2021.
Prior Publication US 2022/0406080 A1, Dec. 22, 2022
Int. Cl. G06V 20/69 (2022.01); G06T 7/00 (2017.01)
CPC G06V 20/698 (2022.01) [G06T 7/0012 (2013.01); G06T 2207/10064 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A cell analysis apparatus, comprising:
image capture circuitry configured to capture a brightfield image of a cell using brightfield imaging, wherein the cell has been dyed by a functional dye that indicates, during fluorescence imaging and during brightfield imaging, whether the cell has a given characteristic;
storage circuitry configured to store a model derived by machine learning; and
processing circuitry configured to use the model in combination with the brightfield image to determine whether the cell has the given characteristic,
wherein the model has been trained with a plurality of fluorescence images and a corresponding plurality of brightfield images, and
wherein the model is further trained using the plurality of fluorescent images to determine whether the given characteristic is present or not in the corresponding plurality of brightfield images.