US 12,223,751 B2
Self-test for imaging device
Dongyao Li, Pleasanton, CA (US); William Nitsch, Pleasanton, CA (US); Neil Ira Weisenfeld, Pleasanton, CA (US); Reynaldo Farias Zorrilla, Pleasanton, CA (US); Pratomo Putra Alimsijah, Pleasanton, CA (US); Augusto Manuel Tentori, Dublin, CA (US); Ashkan Beyranvand Nejad, Pleasanton, CA (US); and Denis Pristinski, Pleasanton, CA (US)
Assigned to 10x Genomics, Inc., Pleasanton, CA (US)
Filed by 10x Genomics, Inc., Pleasanton, CA (US)
Filed on Jun. 18, 2024, as Appl. No. 18/746,750.
Application 18/746,750 is a continuation of application No. PCT/US2022/053395, filed on Dec. 19, 2022.
Claims priority of provisional application 63/291,922, filed on Dec. 20, 2021.
Prior Publication US 2024/0404301 A1, Dec. 5, 2024
Int. Cl. G06V 20/69 (2022.01); G06T 7/80 (2017.01)
CPC G06V 20/69 (2022.01) [G06T 7/80 (2017.01)] 18 Claims
OG exemplary drawing
 
1. A method of self-testing an imaging system of a sample handling apparatus, comprising:
mounting a self-test slide within a sample handling apparatus including an imaging system, wherein the mounted self-test slide is positioned with respect to an image sensor of the imaging system, the self-test slide comprising a pattern positioned on an optically transparent substrate, wherein the pattern includes an array of first features and at least one second feature including a reference side, wherein the array of first features has a minimum linear density greater than or equal to four pixels, and wherein the reference side is rotated at a non-zero angle with respect to an edge of the image sensor;
acquiring, by the image sensor, image data representing a single image of the pattern;
receiving, by a data processor, the single image of the pattern;
determining, by the data processor based upon the received single image of the pattern, at least one of a linear distortion error or a non-linear distortion error for an optical system;
comparing, by the data processor, at least one of the determined linear distortion error or the non-linear distortion error to a corresponding registration error threshold; and
outputting, by the data processor, a first annunciation when at least one of the determined linear distortion error or the non-linear distortion error is greater than or equal to the corresponding registration error threshold, and outputting, by the data processor, a second annunciation, different than the first annunciation, when the at least one of determined linear distortion error or the non-linear distortion error is less than the corresponding registration error.