US 12,222,361 B2
Method for dispensing a liquid sample by means of a dispensing apparatus
Andre Gross, Freiburg (DE); Julian Riba, Freiburg (DE); and Jonas Schöndube, Freiburg (DE)
Assigned to CYTENA GMBH, Freiburg (DE)
Appl. No. 17/780,045
Filed by cytena GmbH, Freiburg (DE)
PCT Filed Nov. 27, 2020, PCT No. PCT/EP2020/083662
§ 371(c)(1), (2) Date May 26, 2022,
PCT Pub. No. WO2021/105380, PCT Pub. Date Jun. 3, 2021.
Claims priority of application No. 101494 (LU), filed on Nov. 27, 2019.
Prior Publication US 2022/0413002 A1, Dec. 29, 2022
Int. Cl. G01N 35/10 (2006.01); B01L 3/02 (2006.01); G01N 15/10 (2024.01)
CPC G01N 35/1016 (2013.01) [B01L 3/0293 (2013.01); G01N 15/10 (2013.01); G01N 2015/1006 (2013.01)] 27 Claims
OG exemplary drawing
 
1. A method for dispensing a liquid sample (22) by a dispensing apparatus (8), comprising steps of:
making a determination as to whether a particle condition is satisfied, wherein making the determination comprises checking whether at least one target particle (4) present in a liquid (5) of the liquid sample (22) is contained in a monitoring region (3) of the dispensing apparatus (8), wherein the monitoring region (3) comprises a discharge region (6) and a buffer region (9), wherein the buffer region (9) is a region from which the at least one target particle (4) is movable into the discharge region (6) during a time delay between the determination of whether the particle condition is satisfied and an output operation of the dispensing apparatus (8), wherein the particle condition is determined to be satisfied when the at least one target particle (4) is arranged in the buffer region (9) and no target particle (4) of the at least one target particle (4) is arranged in the discharge region (6), and
dispensing the liquid sample (22) onto a target particle carrier (11) if the particle condition is determined to be satisfied.