US 12,221,444 B2
5,6,7,7a-tetrahydrocyclopenta[f]pyrido[1,2-h][1,7]naphthyridin-11(4bH)-one compounds and methods of use
John G. Catalano, Research Triangle Park, NC (US); Pek Yoke Chong, Research Triangle Park, NC (US); Hamilton D. Dickson, Research Triangle Park, NC (US); Martin R. Leivers, Research Triangle Park, NC (US); and Jason Gordon Weatherhead, Research Triangle Park, NC (US)
Assigned to GlaxoSmithKline Intellectual Property Development Limited, (GB)
Filed by GLAXOSMITHKLINE INTELLECTUAL, Middlesex (GB)
Filed on Oct. 25, 2021, as Appl. No. 17/509,769.
Application 17/509,769 is a continuation of application No. 16/753,645, abandoned, previously published as PCT/IB2018/057767, filed on Oct. 5, 2018.
Claims priority of provisional application 62/683,859, filed on Jun. 12, 2018.
Claims priority of provisional application 62/681,146, filed on Jun. 6, 2018.
Claims priority of provisional application 62/570,509, filed on Oct. 10, 2017.
Claims priority of provisional application 62/568,633, filed on Oct. 5, 2017.
Prior Publication US 2022/0144834 A1, May 12, 2022
Int. Cl. C07D 471/14 (2006.01); A61P 31/20 (2006.01); C07D 471/20 (2006.01)
CPC C07D 471/14 (2013.01) [A61P 31/20 (2018.01)] 9 Claims
 
1. A compound having the structure:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof.
 
2. A compound having the structure:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof.