US 12,221,423 B1
3-(3-fluorophenyl)-5-(4-methoxybenzylthio)-4-phenyl-4H-1,2,4-triazole as an antimicrobial compound
Hany Mohamed Abd El-Lateef Ahmed, Al-Ahsa (SA); Mai Mostafa Khalaf Ali, Al-Ahsa (SA); and Antar Ahmed Abdelhamid Ahmed, Al-Ahsa (SA)
Assigned to KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed by KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed on Mar. 15, 2024, as Appl. No. 18/606,778.
Application 18/606,778 is a division of application No. 18/382,812, filed on Oct. 23, 2023, abandoned.
Int. Cl. C07D 249/12 (2006.01); A61P 31/04 (2006.01); A61P 31/10 (2006.01)
CPC C07D 249/12 (2013.01) [A61P 31/04 (2018.01); A61P 31/10 (2018.01)] 1 Claim
 
1. A method of treating a microbial infection in a patient comprising administering to a patient in need thereof a therapeutically effective amount of a 3-(3-fluorophenyl)-5-(4-methoxybenzylthio)-4-phenyl-4H-1,2,4-triazole compound having the formula I:

OG Complex Work Unit Chemistry
wherein the microbial infection is caused by one or more gram positive bacteria selected from the group consisting of Bacillus cereus and Staphylococcus aureus;
wherein the microbial infection is caused by one or more gram negative bacteria selected from the group consisting of Pseudomonas aeruginosa and Escherichia coli; or
wherein the microbial infection is caused by one or more fungi selected from the group consisting of Aspergillus flavus and Chrysosporium keratinophilum.