	US 12,221,419 B2
	Abietanes and methods of making and using the same
James H. Frederich, Tallahassee, FL (US); and Megan M. Solans, Tallahassee, FL (US)
Assigned to Florida State University Research Foundation, Inc., Tallahassee, FL (US)
Filed by Florida State University Research Foundation, Incorporated., Tallahassee, FL (US)
Filed on Mar. 30, 2023, as Appl. No. 18/192,703.
Claims priority of provisional application 63/362,160, filed on Mar. 30, 2022.
Prior Publication US 2024/0140912 A1, May 2, 2024
Int. Cl. C07C 13/68 (2006.01); C07C 22/08 (2006.01); C07C 25/22 (2006.01); C07C 35/44 (2006.01); C07C 43/215 (2006.01); C07C 49/753 (2006.01); C07C 49/755 (2006.01); C07D 215/06 (2006.01); C07D 215/227 (2006.01); C07D 307/79 (2006.01)

CPC C07D 215/227 (2013.01) [C07C 13/68 (2013.01); C07C 22/08 (2013.01); C07C 25/22 (2013.01); C07C 35/44 (2013.01); C07C 43/215 (2013.01); C07C 49/753 (2013.01); C07C 49/755 (2013.01); C07D 215/06 (2013.01); C07D 307/79 (2013.01); C07C 2603/40 (2017.05)]

30 Claims

1. A compound having the structure IV or a pharmaceutically acceptable salt or ester thereof

wherein R¹-R⁶are independently hydrogen, a halide, a substituted or unsubstituted alkyl group, an alkoxy group, or a hydroxy group,

R⁷and R⁸are independently hydrogen, a halide, a substituted or unsubstituted alkyl group, or an alkoxy group,

R²⁰is an unsubstituted alkyl group, and

the compound is not taxodione.