US 12,221,410 B2
Method for preparing pinacolone
Wei Cheng, Heze (CN); Fengke Yang, Heze (CN); Zhiyuan Zhao, Heze (CN); Shoufeng Li, Heze (CN); He Ma, Heze (CN); Xinfang Ge, Heze (CN); Yinuo Wei, Heze (CN); Yanchao Yin, Heze (CN); and Li Liu, Heze (CN)
Assigned to HEZE BRANCH, QILU UNIVERSITY OF TECHNOLOGY(SHANDONG ACADEMY OF SCIENCES), Heze (CN)
Filed by HEZE BRANCH, QILU UNIVERSITY OF TECHNOLOGY(SHANDONG ACADEMY OF SCIENCES), Heze (CN)
Filed on May 17, 2024, as Appl. No. 18/667,200.
Application 18/667,200 is a continuation of application No. PCT/CN2022/094219, filed on May 20, 2022.
Claims priority of application No. 202111388133.7 (CN), filed on Nov. 22, 2021.
Prior Publication US 2024/0360064 A1, Oct. 31, 2024
Int. Cl. C07C 45/45 (2006.01); B01J 23/10 (2006.01); C07C 17/08 (2006.01)
CPC C07C 45/45 (2013.01) [B01J 23/10 (2013.01); C07C 17/08 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A method for preparing pinacolone, comprising:
reacting raw materials in the presence of a catalyst to produce pinacolone;
wherein the raw materials comprise 2-methyl-2-butene, hydrochloric acid and formaldehyde;
the catalyst is a single lanthanide Lewis acid, a compounded lanthanide Lewis acid, or a lanthanide metal oxide soluble in hydrochloric acid;
the single lanthanide Lewis acid is selected from the group consisting of lanthanum chloride, cerium chloride, praseodymium chloride and neodymium chloride;
the compounded lanthanide Lewis acid is a combination of a first component and a second component; wherein the first component is selected from the group consisting of lanthanum chloride, cerium chloride, praseodymium chloride and neodymium chloride; the second component is selected from the group consisting of lanthanum chloride, cerium chloride, praseodymium chloride, neodymium chloride, erbium chloride, holmium chloride, dysprosium chloride, thulium chloride, and a combination thereof; and the second component is free of a compound selected as the first component;
a molar ratio of the first component to the second component in the compounded lanthanide Lewis acid is 1-50:50-1; and
in a case that the second component is a combination of two compounds respectively selected from the group consisting of lanthanum chloride, cerium chloride, praseodymium chloride, neodymium chloride, erbium chloride, holmium chloride, dysprosium chloride and thulium chloride, a molar ratio of the first component to one of the two compounds to the other of the two compounds is 1-5:1-3:1-3.