	US 12,221,403 B2
	N^ε-long chain acyl lysine crystal production method and composition containing said crystals
Shuvendu Biswas, Kawasaki (JP); and Naoya Yamato, Kawasaki (JP)
Assigned to AJINOMOTO CO., INC., Tokyo (JP)
Filed by AJINOMOTO CO., INC., Tokyo (JP)
Filed on Dec. 27, 2021, as Appl. No. 17/646,027.
Application 17/646,027 is a continuation of application No. PCT/JP2020/024572, filed on Jun. 23, 2020.
Claims priority of application No. 2019-119387 (JP), filed on Jun. 27, 2019.
Prior Publication US 2022/0119343 A1, Apr. 21, 2022
Int. Cl. C07C 233/47 (2006.01); A61K 8/02 (2006.01); A61K 8/42 (2006.01)

CPC C07C 233/47 (2013.01) [A61K 8/022 (2013.01); A61K 8/42 (2013.01); A61K 2800/622 (2013.01); C07B 2200/13 (2013.01)]

21 Claims

1. An N^ε-lauroyl lysine crystal or a mixture crystal of N^ε-octanoyl lysine and N^ε-lauroyl lysine, wherein a 90% particle diameter D90 of a number-based distribution is 2.8 μm or less.