US 12,220,703 B2
Multi function spinning platform
Anja Boisen, Birkerød (DK); En-Te Hwu, Kgs. Lyngby (DK); Kinga Iudith Zor, Lund (SE); Sriram Thoppe Ranjendran, Holte (DK); and Laura Serioli, Frederiksberg (DK)
Assigned to Danmarks Tekniske Universitet, Kongens Lyngby (DK)
Filed by Danmarks Tekniske Universitet, Kgs. Lyngby (DK)
Filed on Dec. 20, 2021, as Appl. No. 17/555,691.
Application 17/555,691 is a continuation of application No. 17/288,152, previously published as PCT/EP2019/079115, filed on Oct. 24, 2019.
Claims priority of application No. 18202261 (EP), filed on Oct. 24, 2018.
Prior Publication US 2022/0111384 A1, Apr. 14, 2022
Int. Cl. B01L 3/00 (2006.01); B04B 5/12 (2006.01); G01N 21/65 (2006.01); G01N 27/27 (2006.01); G01N 27/327 (2006.01)
CPC B01L 3/502753 (2013.01) [B04B 5/12 (2013.01); G01N 21/65 (2013.01); G01N 27/27 (2013.01); G01N 27/327 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0642 (2013.01); B01L 2200/10 (2013.01); B01L 2200/18 (2013.01); B01L 2300/023 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0803 (2013.01); B01L 2300/12 (2013.01); B01L 2400/0409 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A centrifugal microfluidic disc comprising:
an inlet reservoir;
at least one inlet channel;
at least one sample chamber for in vitro studies of microorganisms;
an inoculation channel for placement of an inoculum in a sample chamber of the at least one sample chamber;
at least one effluent channel; and
an outlet reservoir;
wherein the microfluidic disc is configured for engaging with a rotatable platform or a motor for spinning the microfluidic disc, and wherein the disc is configured such that during rotation of the disc, liquid in the inlet reservoir will be centrifugally forced outwards such that liquid can be controllably transferred from the inlet reservoir to the outlet reservoir via 1) the inlet channel, 2) the sample chamber and 3) the effluent channel, wherein the geometry of the inlet reservoir and the outlet reservoir resembles an arc of a circle, wherein the center of the circle is located at the center of the disc.