US 12,220,698 B2
Microfluidic chip, and apparatus and method for detecting biomolecules
Moon Seong Park, Suwon-si (KR); Kak Namkoong, Seoul (KR); and Won Jong Jung, Seoul (KR)
Assigned to SAMSUNG ELECTRONICS CO., LTD., Suwon-si (KR)
Filed by SAMSUNG ELECTRONICS CO., LTD., Suwon-si (KR)
Filed on Jun. 9, 2021, as Appl. No. 17/343,409.
Claims priority of application No. 10-2020-0079882 (KR), filed on Jun. 30, 2020; and application No. 10-2021-0028301 (KR), filed on Mar. 3, 2021.
Prior Publication US 2021/0402396 A1, Dec. 30, 2021
Int. Cl. G01N 21/64 (2006.01); B01L 3/00 (2006.01); B01L 7/00 (2006.01)
CPC B01L 3/502715 (2013.01) [B01L 3/567 (2013.01); B01L 7/52 (2013.01); G01N 21/6486 (2013.01); B01L 2200/0684 (2013.01); B01L 2200/10 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/069 (2013.01); B01L 2300/16 (2013.01); B01L 2300/1822 (2013.01); B01L 2400/06 (2013.01); G01N 2201/0231 (2013.01)] 31 Claims
OG exemplary drawing
 
1. A microfluidic chip comprising:
a first storage configured to accommodate a sample, the sample comprising target materials;
a plurality of second storages connected to the first storage, the plurality of second storages comprising reactants for the target materials;
a plurality of well arrays connected to the plurality of second storages, respectively, and configured to accommodate a solution of the sample, in which the reactants for the target materials are dissolved;
a plurality of first channels respectively connecting the plurality of second storages and the plurality of well arrays, and a plurality of first valves disposed at the plurality of first channels and configured to control a fluid flow from the plurality of second storages to the plurality of well arrays; and
a plurality of second channels respectively connecting the plurality of well arrays and a structure configured to control a velocity of an inflow of the sample, and a plurality of second valves disposed at the plurality of second channels and configured to control a fluid flow from the plurality of well arrays to the structure, wherein the structure includes at least one of an absorption pad, a vacuum pump, an active pump, or a capillary pump.