US 12,220,667 B2
Organic solvent method for preparing membrane protein based nanosheets and membranes based on nanosheets
Manish Kumar, State College, PA (US); Tingwei Ren, State College, PA (US); Woochul Song, State College, PA (US); and Yu-Ming Tu, State College, PA (US)
Assigned to THE PENN STATE RESEARCH FOUNDATION, University Park, PA (US)
Filed by THE PENN STATE RESEARCH FOUNDATION, University Park, PA (US)
Filed on Dec. 21, 2021, as Appl. No. 17/645,380.
Application 17/645,380 is a division of application No. 16/414,517, filed on May 16, 2019, granted, now 11,235,286.
Claims priority of provisional application 62/672,309, filed on May 16, 2018.
Prior Publication US 2022/0118408 A1, Apr. 21, 2022
Int. Cl. B01D 67/00 (2006.01); B01D 69/14 (2006.01); B01D 71/24 (2006.01); B01D 71/26 (2006.01); B01D 71/52 (2006.01); B01D 71/56 (2006.01); B01D 71/80 (2006.01); C07K 14/245 (2006.01); C07K 14/31 (2006.01); C07K 14/47 (2006.01)
CPC B01D 67/00091 (2022.08) [B01D 69/144 (2013.01); B01D 71/24 (2013.01); B01D 71/261 (2022.08); B01D 71/5211 (2022.08); B01D 71/56 (2013.01); B01D 71/80 (2013.01); C07K 14/245 (2013.01); C07K 14/31 (2013.01); C07K 14/47 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A nanosheet comprising:
a block copolymer, an organic solvent, and a membrane protein comprising a pore or channel structure; wherein the pore or channel structure of the membrane protein is maintained in the nanosheet; wherein the nanosheet does not exhibit crystalline structure; wherein the organic solvent is selected from the group consisting of chloroform, decane, dodecane, heptane, hexane, methanol, or a mixture thereof; and wherein the block copolymer comprises one or more hydrophobic blocks and one or more hydrophilic blocks.