US 12,220,587 B2
Heart rate indicated atrioventricular delay optimization
Qi An, Shoreview, MN (US); Yinghong Yu, Shoreview, MN (US); and Adam MacEwen, White Bear Lake, MN (US)
Assigned to Cardiac Pacemakers, Inc., St. Paul, MN (US)
Filed by Cardiac Pacemakers, Inc., St. Paul, MN (US)
Filed on Oct. 24, 2023, as Appl. No. 18/383,120.
Application 18/383,120 is a continuation of application No. 17/559,770, filed on Dec. 22, 2021, granted, now 11,850,430.
Application 17/559,770 is a continuation of application No. 16/694,229, filed on Nov. 25, 2019, granted, now 11,235,157.
Claims priority of provisional application 62/779,792, filed on Dec. 14, 2018.
Prior Publication US 2024/0050754 A1, Feb. 15, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. A61N 1/365 (2006.01); A61N 1/362 (2006.01); A61N 1/368 (2006.01)
CPC A61N 1/36592 (2013.01) [A61N 1/3627 (2013.01); A61N 1/3682 (2013.01); A61N 1/36843 (2017.08)] 20 Claims
OG exemplary drawing
 
1. A medical system, comprising:
a memory configured to store (i) a regression model representing a relationship between values of an atrioventricular conduction characteristic and a plurality of heart rates or heart rate ranges, and (ii) values of one or more stimulation parameters;
an electrostimulator configured to generate electrostimulation energy in accordance with the one or more stimulation parameters; and
a controller circuit configured to:
receive a sensed heart rate in a patient;
estimating the atrioventricular conduction characteristic at the sensed heart rate using the stored regression model;
update at least one of the stored one or more stimulation parameters using the estimated atrioventricular conduction characteristic; and
generate a control signal to the electrostimulator to output the electrostimulation energy in accordance with the updated at least one of the stored one or more stimulation parameters.