US 12,220,579 B2
Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
Kirk R. Manogue, Sea Cliff, NY (US)
Assigned to The Feinstein Institutes for Medical Research, Manhasset, NY (US)
Filed by The Feinstein Institutes for Medical Research, Manhasset, NY (US)
Filed on Jan. 18, 2022, as Appl. No. 17/578,339.
Application 17/578,339 is a continuation of application No. 16/582,726, filed on Sep. 25, 2019, granted, now 11,260,229.
Claims priority of provisional application 62/736,447, filed on Sep. 25, 2018.
Prior Publication US 2022/0212012 A1, Jul. 7, 2022
Int. Cl. A61N 1/36 (2006.01); A61N 1/04 (2006.01); A61N 1/05 (2006.01)
CPC A61N 1/36053 (2013.01) [A61N 1/0456 (2013.01); A61N 1/0526 (2013.01); A61N 1/36017 (2013.01); A61N 1/36036 (2017.08); A61N 1/3606 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A device for reducing bleed time in a subject by simultaneously concurrently stimulating both a vagus nerve and a trigeminal nerve, the device comprising:
a housing configured to fit on or in an auricle region of an ear of the subject;
a vagus stimulator coupled to the housing and configured to be applied to the ear;
a trigeminal stimulator coupled to the housing and configured to be applied to the subject's face or head over a region innervated by the trigeminal nerve; and
a controller within the housing, the controller comprising control circuitry, power control circuitry, a waveform generator, a trigeminal stimulation drive and a vagus stimulation drive, wherein the control circuitry is configured to control the trigeminal stimulation drive and the vagus stimulation drive to coordinate concurrent application of activation from both the vagus stimulator and the trigeminal stimulator in a stimulation pattern configured to reduce bleed time in a subject.