US 12,220,539 B2
Anti-infection fluidic channel
Tingtao Zhou, Los Angeles, CA (US); Xuan Wan, Pasadena, CA (US); Paul W. Sternberg, San Marino, CA (US); Chiara Daraio, South Pasadena, CA (US); Zhengyu Huang, Beijing (CN); Zongyi Li, Alhambra, CA (US); Zhiwei Peng, Mississauga (CA); John F. Brady, Pasadena, CA (US); and Animashree Anandkumar, Pasadena, CA (US)
Assigned to CALIFORNIA INSTITUTE OF TECHNOLOGY, Pasadena, CA (US)
Filed by CALIFORNIA INSTITUTE OF TECHNOLOGY, Pasadena, CA (US)
Filed on Sep. 25, 2024, as Appl. No. 18/896,646.
Application 18/896,646 is a continuation of application No. 18/604,162, filed on Mar. 13, 2024, granted, now 12,128,189.
Claims priority of provisional application 63/451,788, filed on Mar. 13, 2023.
Claims priority of provisional application 63/602,756, filed on Nov. 27, 2023.
Claims priority of provisional application 63/554,052, filed on Feb. 15, 2024.
Prior Publication US 2025/0018148 A1, Jan. 16, 2025
Int. Cl. A61M 25/00 (2006.01)
CPC A61M 25/0017 (2013.01) [A61M 2025/006 (2013.01)] 7 Claims
OG exemplary drawing
 
1. A method of making a catheter having a urine flow direction, the method comprising:
providing a catheter tube with an inner channel;
providing a plurality of protuberances on an interior surface of the inner channel, each of the protuberances having a first side facing into the flow direction at a first angle from the interior surface and a second side facing away from the flow direction at a second angle from the interior surface and a vertex between the first side and the second side and a base length from where the first side connects to the interior surface to where the second side connects to the interior surface, each of the plurality of protuberances being configured to create vortices during a flow of fluid in the urine flow direction;
the first angle being different from the second angle, such that each protuberance has an asymmetrical profile and wherein the first angle is greater than 90 degrees and the second angle is less than 90 degrees; and
the base length of each of the plurality of protuberances being less than one half the distance between vertices of adjacent protuberances;
wherein the providing the plurality of protuberances comprises optimizing geometry parameters of the plurality of protuberances by a geometric Fourier neural operator model.