US 12,220,502 B2
Medical devices coated with shape memory polymer foams
Rachael Muschalek, College Station, TX (US); Keith Hearon, Boston, MA (US); Landon D. Nash, Sunnyvale, CA (US); and Duncan J. Maitland, College Station, TX (US)
Assigned to The Texas A&M University System, College Station, TX (US)
Filed by The Texas A&M University System, College Station, TX (US)
Filed on Jun. 23, 2022, as Appl. No. 17/847,426.
Application 17/847,426 is a continuation of application No. 16/777,190, filed on Jan. 30, 2020, granted, now 11,369,720.
Application 16/777,190 is a continuation of application No. 15/746,574, granted, now 10,561,765, issued on Feb. 18, 2020, previously published as PCT/US2016/043711, filed on Jul. 22, 2016.
Claims priority of provisional application 62/197,181, filed on Jul. 27, 2015.
Prior Publication US 2022/0395615 A1, Dec. 15, 2022
Int. Cl. A61L 31/10 (2006.01); A61L 17/14 (2006.01); A61L 27/34 (2006.01); A61L 27/56 (2006.01); A61L 31/14 (2006.01)
CPC A61L 31/10 (2013.01) [A61L 17/145 (2013.01); A61L 27/34 (2013.01); A61L 27/56 (2013.01); A61L 31/146 (2013.01); A61L 2400/16 (2013.01); A61L 2430/36 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A system comprising:
a substrate of a medical device;
an un-foamed, hydrophilic, aliphatic coating on the substrate and fixedly attached to the substrate;
a thermoset polyurethane shape memory polymer (SMP) foam, having a primary state and a programmed secondary state, which directly contacts the coating and fixedly attaches to the coating;
wherein:
the coating fixedly attaches the SMP foam to the substrate;
the SMP foam is in the primary state;
the SMP foam has first and second portions that each include cells the first portion being directly between the second portion and the coating;
the SMP foam includes a reaction product of triethanolamine (TEA) and hexamethylene diisocyanate (HDI); the cells of the first portion have a first average cell diameter; and the cells of the second portion have a second average cell diameter that is greater than the first average cell diameter.