	US 12,220,459 B2
	Immune-stimulatory compositions and use thereof
Jeroen Van Bergen, Leiden (NL); and Gerben Carolus Martinus Zondag, Leiden (NL)
Assigned to Nykode Therapeutics ASA, Oslo (NO)
Appl. No. 17/600,164
Filed by Nykode Therapeutics ASA, Oslo (NO)
PCT Filed Apr. 2, 2020, PCT No. PCT/NL2020/050225 § 371(c)(1), (2) Date Sep. 30, 2021, PCT Pub. No. WO2020/204714, PCT Pub. Date Oct. 8, 2020.
Claims priority of application No. 19166877 (EP), filed on Apr. 2, 2019.
Prior Publication US 2022/0211843 A1, Jul. 7, 2022
Int. Cl. A61K 39/39 (2006.01); A61K 39/00 (2006.01)

CPC A61K 39/39 (2013.01) [A61K 2039/55516 (2013.01); A61K 2039/55527 (2013.01)]

22 Claims

1. A constitutively active pro-inflammatory caspase-1, comprising swapped p10 and p20 domains.