	US 12,220,448 B2
	Method of treating pathogenic bacterial infectious diseases
Jung Min Kim, Daegu (KR); Jong Sook Jin, Daegu (KR); and Shukho Kim, Daegu (KR)
Assigned to KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, Daegu (KR)
Appl. No. 17/262,184
Filed by KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, Daegu (KR)
PCT Filed Aug. 28, 2019, PCT No. PCT/KR2019/011018 § 371(c)(1), (2) Date Jul. 11, 2021, PCT Pub. No. WO2020/055011, PCT Pub. Date Mar. 19, 2020.
Claims priority of application No. 10-2018-0108202 (KR), filed on Sep. 11, 2018.
Prior Publication US 2022/0175894 A1, Jun. 9, 2022
Int. Cl. A61K 38/47 (2006.01); A01N 63/50 (2020.01); A23K 20/147 (2016.01); A23L 33/17 (2016.01); A61P 31/04 (2006.01); C12N 7/00 (2006.01); A01P 1/00 (2006.01)

CPC A61K 38/47 (2013.01) [A01N 63/50 (2020.01); A23K 20/147 (2016.05); A23L 33/17 (2016.08); A61P 31/04 (2018.01); C12N 7/00 (2013.01); C12Y 302/01017 (2013.01); A01P 1/00 (2021.08); A23V 2002/00 (2013.01); C12N 2795/10322 (2013.01); C12N 2795/10333 (2013.01)]

2 Claims

1. A method of treating a pathogenic bacterial infectious disease, comprising:

administering to a subject a pharmaceutical composition comprising a LysSAP26 protein,

wherein the LysSAP26 protein has the amino acid sequence set forth in SEQ ID NO: 1 and a pharmaceutically acceptable carrier,

wherein the pathogenic bacterial infectious disease is caused by carbapenem-resistant Acinetobacter baumannii (CRAB), and is selected from the group consisting of sepsis, impetigo, purulent disease, and wound infection, and

wherein the LysSAP26 protein is obtained from a bacteriophage SAP26 of Siphoviridae deposited as Accession Number KCTC 11665BP.