	US 12,220,439 B2
	Methods of diagnosing and treating dry eye syndrome and compositions for treating a human eye
Scott Whitcup, Laguna Hills, CA (US); Orest Olejnik, Reno, NV (US); Michael Garst, Newport Beach, CA (US); and Peter Simmons, Yorba Linda, CA (US)
Assigned to Akrivista LLC, Irvine, CA (US)
Filed by Akrivista LLC, Irvine, CA (US)
Filed on Mar. 31, 2023, as Appl. No. 18/129,182.
Application 18/129,182 is a continuation of application No. 16/638,546, granted, now 11,622,982, previously published as PCT/US2018/046918, filed on Aug. 17, 2018.
Claims priority of provisional application 62/547,553, filed on Aug. 18, 2017.
Prior Publication US 2023/0233637 A1, Jul. 27, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61P 27/04 (2006.01); A61K 9/00 (2006.01); A61K 9/107 (2006.01); A61K 36/235 (2006.01); A61K 36/47 (2006.01); A61K 36/534 (2006.01); A61K 36/54 (2006.01); A61K 36/61 (2006.01); A61K 36/752 (2006.01); A61K 47/32 (2006.01); A61K 47/44 (2017.01); G01N 33/50 (2006.01)

CPC A61K 36/235 (2013.01) [A61K 9/0048 (2013.01); A61K 9/1075 (2013.01); A61K 36/47 (2013.01); A61K 36/534 (2013.01); A61K 36/54 (2013.01); A61K 36/61 (2013.01); A61K 36/752 (2013.01); A61K 47/32 (2013.01); A61K 47/44 (2013.01); A61P 27/04 (2018.01); G01N 33/50 (2013.01)]

20 Claims

1. A composition for applying to an eye or eyelid of a human comprising:

water;

0.1% (w/v) to 0.3% (w/v), inclusive, of a hydrophobic component, wherein the hydrophobic component comprises from about 0.05% (w/v) to about 0.25% (w/v) avocado oil and from about 0.05% (w/v) to about 0.25% (w/v) castor oil; and

hyaluronic acid.