|
US 12,220,431 B2 |
|
| Gamma polyglutamated antifolates and uses thereof |
| Clet Niyikiza, Gulph Mills, PA (US); and Victor Mandla Moyo, Ringoes, NJ (US) |
| Assigned to L.E.A.F. HOLDINGS GROUP LLC, Gulph Mills, PA (US) |
| Appl. No. 16/967,214 |
| Filed by L.E.A.F. HOLDINGS GROUP LLC, Gulph Mills, PA (US) |
PCT Filed Feb. 7, 2019, PCT No. PCT/US2019/017004
§ 371(c)(1), (2) Date Aug. 4, 2020,
PCT Pub. No. WO2019/157148, PCT Pub. Date Aug. 15, 2019. |
| Claims priority of provisional application 62/764,945, filed on Aug. 17, 2018. |
| Claims priority of provisional application 62/764,951, filed on Aug. 17, 2018. |
| Claims priority of provisional application 62/702,774, filed on Jul. 24, 2018. |
| Claims priority of provisional application 62/702,779, filed on Jul. 24, 2018. |
| Claims priority of provisional application 62/662,372, filed on Apr. 25, 2018. |
| Claims priority of provisional application 62/636,751, filed on Feb. 28, 2018. |
| Claims priority of provisional application 62/636,289, filed on Feb. 28, 2018. |
| Claims priority of provisional application 62/630,824, filed on Feb. 14, 2018. |
| Claims priority of provisional application 62/630,652, filed on Feb. 14, 2018. |
| Claims priority of provisional application 62/630,613, filed on Feb. 14, 2018. |
| Claims priority of provisional application 62/630,620, filed on Feb. 14, 2018. |
| Claims priority of provisional application 62/630,625, filed on Feb. 14, 2018. |
| Claims priority of provisional application 62/627,733, filed on Feb. 7, 2018. |
| Claims priority of provisional application 62/627,732, filed on Feb. 7, 2018. |
| Prior Publication US 2020/0360389 A1, Nov. 19, 2020 |
| This patent is subject to a terminal disclaimer. |
| Int. Cl. A61K 33/243 (2019.01); A61K 9/127 (2006.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01); A61K 47/55 (2017.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01) |