US 12,219,974 B2
Probiotic for poultry or cud-chewing animals
Eric Auclair, Avelin (FR); Christine Julien, Sepx (FR); and Jean-Philippe Marden, Labege (FR)
Assigned to LESAFFRE ET COMPAGNIE, Paris (FR)
Appl. No. 17/055,354
Filed by LESAFFRE ET COMPAGNIE, Paris (FR)
PCT Filed May 14, 2019, PCT No. PCT/FR2019/051097
§ 371(c)(1), (2) Date Nov. 13, 2020,
PCT Pub. No. WO2019/220052, PCT Pub. Date Nov. 21, 2019.
Claims priority of application No. 1854046 (FR), filed on May 15, 2018.
Prior Publication US 2021/0219568 A1, Jul. 22, 2021
Int. Cl. A23K 10/18 (2016.01); A23K 50/10 (2016.01); A23K 50/75 (2016.01); C12N 1/18 (2006.01); C12R 1/865 (2006.01)
CPC A23K 10/18 (2016.05) [A23K 50/10 (2016.05); A23K 50/75 (2016.05); C12N 1/185 (2021.05); C12R 2001/865 (2021.05)] 9 Claims
 
1. A method for improving the growth and weight gain performances and the consumption index (CI) of poultry, comprising administering to a poultry animal an effective amount of a Saccharomyces cerevisiae active yeast adapted to a weak organic acid chosen from propionic acid and its salts, wherein:
said adapted Saccharomyces cerevisiae active yeast is obtained by the adaptation of a Saccharomyces cerevisiae active yeast derived from a strain chosen from the strains deposited at the CNCM under number I-5128 and I-5131 on Aug. 31, 2016, to the presence of a weak organic acid carried out during the final hours of a final multiplication stage by addition of 0.1 g to 10 g of weak organic acid and/or salts thereof, per liter of culture medium, so as to obtain between 1500 and 3000 ppm of weak organic acid by weight in the culture medium;
a ratio of a volume of CO2 given off for 2 hours of culture from said adapted Saccharomyces cerevisiae active yeast derived from the strain chosen from I-5128 and I-5131 to a volume of CO2 given off for 2 hours of culture from a non-adapted Saccharomyces cerevisiae active yeast derived from the strain chosen from I-5128 and I-5131 is greater than or equal to 1; and
said adapted Saccharomyces cerevisiae active yeast has an increased tolerance to a weak organic acid by virtue of a first exposure to said weak organic acid during the final multiplication stage such that said adapted Saccharomyces cerevisiae active yeast has a growth and a fermentative capacity of that are not inhibited when said adapted Saccharomyces cerevisiae active yeast is in the presence of said weak organic acid for at least a second exposure.