	US 12,219,955 B2
	Antimicrobial layered material
Klaus-Dieter Vissing, Bremen (DE); Dirk Salz, Bremen (DE); and Peter Steinrücke, Nuremberg (DE)
Assigned to Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., Munich (DE); and Bio-Gate AG, Nuremberg (DE)
Appl. No. 16/954,402
Filed by Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., Munich (DE); and Bio-Gate AG, Nuremberg (DE)
PCT Filed Dec. 18, 2018, PCT No. PCT/EP2018/085470 § 371(c)(1), (2) Date Jun. 16, 2020, PCT Pub. No. WO2019/121667, PCT Pub. Date Jun. 27, 2019.
Claims priority of application No. 10 2017 130 600.5 (DE), filed on Dec. 19, 2017.
Prior Publication US 2021/0078311 A1, Mar. 18, 2021
Int. Cl. B32B 27/14 (2006.01); A01N 25/34 (2006.01); A01N 59/16 (2006.01); A01N 59/20 (2006.01)

CPC A01N 25/34 (2013.01) [A01N 59/16 (2013.01); A01N 59/20 (2013.01)]

11 Claims

1. An antimicrobial layer material comprising:

a biocide layer with a particulate biocidal active ingredient; and

a plasma-polymeric layer as a transport control layer disposed upon the biocide layer;

wherein the antimicrobial layer material includes the biocide layer including a sputtered metallic silver layer having a plurality of silver particles, wherein for over 95% of the plurality of particles, each of the plurality of particles has a limiting size of ≤80 nm, and the plasma-polymeric layer including a transport control layer disposed thereon, the transport control layer having a thickness in a range of ≥5 nm and ≤320 nm, and a ratio of a thickness of the transport control layer to the limiting size of ≥1.4, the transport control layer being generated in an afterglow plasma enhanced-chemical vapor deposition (PE-CVD) method, the after-glow PE-CVD method including a substrate being placed in a parallel-plate reactor for the after-glow PE-CVD method such that a distance between the substrate and a plasma electrode is at least thirty times a dark space zone, and wherein the dark space zone is a cathode trap in which a plasma potential drops to a cathode potential;

wherein the transport control layer has a layer construction characterized by a release property;

wherein the release property is characterized by a decolorization feature which is correlated with a decolorization time of ≤25 minutes per a thickness of the transport control layer of 40 nm when a sample including the antimicrobial layer disposed on a substrate is subjected to a H₂O₂treatment;

wherein the H₂O₂treatment includes covering the transport control layer of the sample with at least 1 cm³of 50% H₂O₂solution per cm²of the transport control layer;

wherein the decolorization time corresponds to a time duration required for an absorption constant of the sample in a wavelength range of 300 nm to 500 nm to have a differential of 0.01 relative to a reference sample including the substrate and the plasma-polymeric layer deposited directly on the substrate without the biocide layer;

wherein the particulate biocidal active ingredient is selected from the group consisting of silver, copper, and zinc; and

wherein the plasma-polymeric layer consists of at least 95 atom % of elements being selected from a group of elements consisting of Ti, O and C; Si, O, C and N; and Si, O and C, based on a total number of atoms determined by XPS.