	US 12,216,121 B2
	Methods and compositions for spacial and temporal measurement of catalytic activity
Yamuna Krishnan, Chicago, IL (US); Krishna Dan, Chicago, IL (US); Aneesh T. Veetil, Chicago, IL (US); and Kasturi Chakraborty, Chicago, IL (US)
Assigned to THE UNIVERSITY OF CHICAGO, Chicago, IL (US)
Appl. No. 16/603,722
Filed by The University of Chicago, Chicago, IL (US)
PCT Filed Apr. 12, 2018, PCT No. PCT/US2018/027391 § 371(c)(1), (2) Date Oct. 8, 2019, PCT Pub. No. WO2018/191561, PCT Pub. Date Oct. 18, 2018.
Claims priority of provisional application 62/484,666, filed on Apr. 12, 2017.
Prior Publication US 2021/0096129 A1, Apr. 1, 2021
Int. Cl. G01N 33/573 (2006.01); C07H 21/04 (2006.01); G01N 21/64 (2006.01)

CPC G01N 33/573 (2013.01) [C07H 21/04 (2013.01); G01N 21/6428 (2013.01)]

18 Claims

1. A composition comprising:

a first nucleic acid; and

a second nucleic acid;

wherein the first nucleic acid and the second nucleic acid are in a nucleic acid duplex;

and wherein the first nucleic acid comprises SEQ ID NO:1 and the second nucleic acid comprises SEQ ID NO:2, or wherein the first nucleic acid comprises SEQ ID NO:2 and the second nucleic acid comprises SEQ ID NO:1.