US 12,215,140 B2
Method of stabilizing protein contained in specimen and solution for stabilizing protein contained in specimen
Nozomi Sakamaki, Tochigi (JP); Hidenori Taguchi, Tochigi (JP); Mitsuru Makinodan, Tochigi (JP); and Miyu Yamada, Tochigi (JP)
Assigned to EIKEN KAGAKU KABUSHIKI KAISHA, Tokyo (JP)
Appl. No. 16/977,338
Filed by EIKEN KAGAKU KABUSHIKI KAISHA, Tokyo (JP)
PCT Filed Feb. 28, 2019, PCT No. PCT/JP2019/007867
§ 371(c)(1), (2) Date Sep. 1, 2020,
PCT Pub. No. WO2019/168109, PCT Pub. Date Sep. 6, 2019.
Claims priority of application No. 2018-037227 (JP), filed on Mar. 2, 2018.
Prior Publication US 2020/0407425 A1, Dec. 31, 2020
Int. Cl. C07K 14/805 (2006.01); G01N 33/72 (2006.01)
CPC C07K 14/805 (2013.01) [G01N 33/72 (2013.01); G01N 33/721 (2013.01)] 19 Claims
 
1. A method of stabilizing a protein contained in a specimen derived from a living body, the method comprising a step of causing the protein contained in the specimen derived from the living body to coexist with an arylboronic acid and a sugar in a solution, wherein
the protein contained in the specimen derived from the living body is at least one selected from the group consisting of hemoglobin, haptoglobin, and a hemoglobin-haptoglobin complex.