US 12,215,132 B2
Methods, compositions and uses thereof for reversing sarcopenia
Gerard Karsenty, New York, NY (US); Julian Berger, New York, NY (US); and Han Xiao, Houston, TX (US)
Assigned to The Trustees of Columbia University in the City of New York, New York, NY (US); and William Marsh Rice University, Houston, TX (US)
Filed by The Trustees of Columbia University in the City of New York, New York, NY (US); and William Marsh Rice University, Houston, TX (US)
Filed on Oct. 18, 2021, as Appl. No. 17/504,158.
Application 17/504,158 is a continuation of application No. PCT/US2021/027942, filed on Apr. 19, 2021.
Claims priority of provisional application 63/011,956, filed on Apr. 17, 2020.
Prior Publication US 2022/0106372 A1, Apr. 7, 2022
Int. Cl. A61K 38/00 (2006.01); A61P 21/06 (2006.01); C07K 14/54 (2006.01); C07K 14/575 (2006.01)
CPC C07K 14/575 (2013.01) [A61P 21/06 (2018.01); C07K 14/5412 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/30 (2013.01)] 4 Claims
 
1. A method for reducing loss of muscle function in a subject with sarcopenia, comprising: administering to the subject a pharmaceutical composition which comprises a therapeutically effective amount of Interleukin-6-Bisphosphonate fusion peptide.