US 12,215,127 B2
Compositions and methods for profiling of gut microbiota-associated bile salt hydrolase (BSH) activity
Pamela Chang, Ithaca, NY (US); Bibudha Parasar, Ithaca, NY (US); and Lin Han, Ithaca, NY (US)
Assigned to CORNELL UNIVERSITY, Ithaca, NY (US)
Filed by CORNELL UNIVERSITY, Ithaca, NY (US)
Filed on Apr. 15, 2021, as Appl. No. 17/231,432.
Claims priority of provisional application 63/011,449, filed on Apr. 17, 2020.
Prior Publication US 2021/0323996 A1, Oct. 21, 2021
Int. Cl. C07J 43/00 (2006.01); G01N 33/68 (2006.01)
CPC C07J 43/003 (2013.01) [G01N 33/6848 (2013.01); G01N 2333/98 (2013.01); G01N 2800/065 (2013.01)] 25 Claims
 
1. A compound having the following structure:

OG Complex Work Unit Chemistry
wherein:
R1 is OH, ester group, ether group, or a group containing an alkynyl or azido functionality;
R2 is H, OH, ester group, ether group, or a group containing an alkynyl or azido functionality;
R3 is a group selected from the group consisting of

OG Complex Work Unit Chemistry
wherein X is a halogen atom; and
R4 is H, OH, ester group, ether group, or a group containing an alkynyl or azido functionality;
wherein one of R1, R2 and R4 is a group containing an alkynyl or azido functionality.