US 12,215,082 B1
(e)-1-(2-(4-substitutedphenyl)-2-oxoethyl)-4-((hydroxyimino)methyl)pyridinium bromides as antitubercular agents
Katharigatta N. Venugopala, Al-Ahsa (SA); Sandeep Chandrashekharappa, Lucknow UP (IN); Melendran Pillay, Durban (CA); Pran Kishore Deb, Ranchi (IN); and Rashmi Venugopala, KwaZulu-Natal (CA)
Assigned to KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed by KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed on Jun. 14, 2024, as Appl. No. 18/743,946.
Application 18/642,112 is a division of application No. 18/386,017, filed on Nov. 1, 2023.
Application 18/743,946 is a continuation of application No. 18/642,112, filed on Apr. 22, 2024, abandoned.
Int. Cl. C07D 213/53 (2006.01); A61P 31/06 (2006.01)
CPC C07D 213/53 (2013.01) [A61P 31/06 (2018.01)] 9 Claims
 
1. A method of treating tuberculosis in a patient, comprising administering to a patient in need thereof a therapeutically effective amount of a compound having the formula I:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt, ester, stereoisomer, or solvate thereof, wherein:
R is selected from the group consisting of hydrogen, halogen, cyano, and nitro.