US 12,214,202 B2
On-line autocalibration method for a computer brain interface device and computer brain interface device
Bálint Várkuti, Munich (DE); Saman Hagh-Gooie, Hamburg (DE); and Brian Blischak, San Diego, CA (US)
Assigned to Ceregate GmbH, Munich (DE)
Filed by CEREGATE GMBH, Munich (DE)
Filed on Apr. 7, 2021, as Appl. No. 17/224,953.
Prior Publication US 2022/0323763 A1, Oct. 13, 2022
Int. Cl. A61N 1/36 (2006.01); G06F 3/01 (2006.01)
CPC A61N 1/36139 (2013.01) [A61N 1/36132 (2013.01); A61N 1/36171 (2013.01); A61N 1/36175 (2013.01); A61N 1/36178 (2013.01); G06F 3/015 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method for self-calibrating a computer brain interface, CBI, device of an individual, the method comprising:
selecting a set of test signal parameters;
generating, based on the selected set of test signal parameters, at least one neurostimulation test signal configured to elicit a bioelectric response in one or more afferent sensory nerve fibers;
applying the generated neurostimulation test signal to the afferent sensory nerve fibers via a neurostimulation interface operably connected to or integrated with the CBI device;
sensing via the neurostimulation interface, one or more bioelectric responses of the one or more stimulated afferent sensory nerve fibers;
determining, based on the sensed bioelectric responses, whether an excitation behavior of the stimulated afferent sensory nerve fibers with respect to the neurostimulation interface has changed;
when the excitation behavior has changed, determining, based on the sensed bioelectric responses, a set of recalibrated neurostimulation signal parameters, wherein determining the set of recalibrated neurostimulation signal parameters comprises comparing the sensed bioelectric responses to a set of reference bioelectric responses stored in a memory module of the CBI device or obtained via a communication interface of the CBI device; and
operating the CBI device, using the recalibrated neurostimulation signal parameters, to communicate information to the individual via neurostimulation of the one or more afferent sensory nerve fibers.