US 12,214,082 B1
One pass spray dried lactose
Richard K. Merrill, Highlands Ranch, CO (US); Neill Burt, Denver, CO (US); and Stephen Charles Secrest, Visalia, CA (US)
Assigned to Leprino Foods Company, Denver, CO (US)
Filed by Leprino Foods Company, Denver, CO (US)
Filed on May 13, 2024, as Appl. No. 18/662,719.
Int. Cl. A61K 9/00 (2006.01); A61K 9/20 (2006.01); C13K 5/00 (2006.01)
CPC A61K 9/2018 (2013.01) [C13K 5/00 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method of making spray dried lactose particles, comprising:
concentrating an aqueous lactose source;
crystallizing at least a portion of the lactose in the concentrated lactose source,
forming a crystallized lactose slurry comprising a plurality of lactose particles by washing the crystallized lactose slurry for a period of time sufficient to reduce an absolute value of a b*-value color of the lactose particles by greater than or about 75%;
wet milling the crystallized lactose slurry, reducing a D50 particle size of the plurality of lactose particles by greater than or about 50%; and
spray drying the crystallized lactose slurry, forming a plurality of spray dried lactose particles.