US 12,214,027 B2
Stabilisation of live mollicutes bacteria in a liquid composition
Martin Piest, Afferden (NL); Edwin Kets, Heilig Landstichting (NL); Paul Vermeij, St. Anthonis (NL); Marian Anna Catharina Jozefina Heijnen, Arcen (NL); and Nöel Dautzenberg, Nijmegen (NL)
Assigned to INTERVET INC., Rahway, NJ (US)
Appl. No. 17/441,768
Filed by Intervet inc., Rahway, NJ (US)
PCT Filed Mar. 27, 2020, PCT No. PCT/EP2020/058649
§ 371(c)(1), (2) Date Sep. 22, 2021,
PCT Pub. No. WO2020/201048, PCT Pub. Date Oct. 8, 2020.
Claims priority of application No. 19166362 (EP), filed on Mar. 29, 2019.
Prior Publication US 2022/0175902 A1, Jun. 9, 2022
Int. Cl. A61K 39/02 (2006.01); A61K 39/00 (2006.01)
CPC A61K 39/0241 (2013.01) [A61K 2039/52 (2013.01); A61K 2039/552 (2013.01)] 14 Claims
 
1. A liquid composition for protection against infection or disease caused by Mollicutes bacteria, comprising live Mollicutes bacteria and a stabiliser, wherein the stabiliser is a natural deep-eutectic solvent (NADES), wherein the composition has a water activity of 0.85 or less, and a water content of 50% w/w or less.